ISSN : 2714-4917


NIGER DELTA JOURNAL OF MEDICINE & MEDICAL RESEARCH

A Publication Of Nigeria Medical Association Bayelsa State Branch

Home About Us For Authors Issues Useful Downloads Contact Information

FAQ NDJMMR

Questions are asked and these questions need answers. This is the reason why this page is created to enable us share few worries!

×
Archive | ISSUE: 157, Volume: Jul-Sep-2026

PREVALENCE OF HELICOBACTER PYLORI INFECTION AMONG SUSPECTED PEPTIC ULCER DISEASE PATIENTS ATTENDING BAZE UNIVERSITY HOSPITAL, ABUJA


Author:Abdullahi N, Abdulrahman FM

published date:2026-Jul-07

FULL TEXT in - | page 81–84

Abstract

Background: Helicobacter pylori is a spiral-shaped gram negative micro-aerophilic bacterium that has been implicated as the causative organism of chronic gastritis, gastric and duodenal ulcer. About 50% of the world population are infected with H pylori. Many epidemiologic studies have shown consistent evidence that people with chronic H. pylori infections have an increased risk of developing non-cardia gastric adenocarcinoma and gastric MALT lymphoma. The prevalence in Nigeria varies between 50% and 87%, with high prevalence observed in the Northern and Southwest of the country.

Objectives: To determine the prevalence of Helicobacter pylori infection among suspected peptic ulcer disease patients attending Baze University Hospital, Abuja.

Materials and Method: This was a retrospective, cross-sectional study done at the department of Medical Microbiology and Parasitology, Baze University Hospital, Abuja, Nigeria, from October 2022 to October 2025. The study involved the review of the medical microbiology laboratory data of both H. pylori stool antigen and serology tests results of suspected peptic ulcer disease patients’ samples.

Results: A total of 316 suspected PUD patients were included in the study with females accounting for 71.2% of the participants. The prevalence rate of H. pylori infection (serology and stool antigens combined) was 50.0% (158/316). The prevalence in the females (36.4%) was three times higher than in the males (13.6%). The age group ≤20 years, accounted for the highest prevalence (30.3%) of H. pylori infection, followed closely by age group 21 – 30 years with 26.6%.

Conclusion: H. pylori infection is prevalent among symptomatic adults in this locality. Screening for H. pylori is recommended for detection, prompt treatment and eradication of the infection to prevent long-term complications.

Keywords: H. pylori prevalence, Baze University Hospital, Abuja ,,

References

1. Pizzorno JE, Murray MT, Joiner-Bey H. Peptic ulcers. In: The clinician’s handbook of natural medicine. St Louis Livingstone/Elsevier; 2008. p. 778–9.

2. Morais S, Costa A, Albuquerque G, Araújo N, Tsugane S, Hidaka A, et al. True Helicobacter pylori infection and non-cardia gastric cancer: a pooled analysis within the Stomach Cancer Pooling (StoP) Project. Helicobacter. 2022;27(2).

3. Han Z, Liu J, Zhang W, Kong Q, Wan M, Lin M, et al. Cardia and non-cardia gastric cancer risk associated with Helicobacter pylori in East Asia and the West: a systematic review, meta-analysis, and estimation of population attributable fraction. Helicobacter. 2023;28(2).

4. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, International Agency for Research on Cancer. Schistosomes, liver flukes and Helicobacter pylori. Geneva: International Agency for Research on Cancer; 1994.

5. Emerenini FC, Nwolisa EC, Iregbu FU, Eke CB, Ikefuna AN. Prevalence and risk factors for Helicobacter pylori infection among children in Owerri, Nigeria. Niger J 2021;24(8):1188–93.

6. Aje AO, Otegbayo JA, Odaibo GN, Bojuwoye BJ. Comparative study of stool antigen test and serology for Helicobacter pylori among Nigerian dyspeptic patients: a pilot study. Niger J Clin Pract. 2010;13(2):120–4.

7. Smith S, Ajayi A, Jolaiya TF, Essiet U. Prevalence, diagnosis and treatment of Helicobacter pylori infection in Nigeria. Niger J Gastroenterol Hepatol. 2022;14(1):2.

8. Gide S, Ibrahim Y, Anas G, Alegbe SD. Prevalence of Helicobacter pylori infection in patients with dyspeptic symptoms in Damaturu Metropolitan. J Adv Microbiol. 2019;1–8.

9. Okoroiwu GIA, Toluhi FG. Prevalence and associated risk factors of Helicobacter pylori among residents of Abuja Municipal Area Council (AMAC), FCT Abuja. Sokoto J Med Lab Sci. 2025;10(1):162–73.

10. Magalhães Queiroz DM, Luzza F. Epidemiology of Helicobacter pylori infection. Helicobacter. 2006;11 Suppl 1:1–5. (MO): Clin Churchill Pract.

11. Irabor M, Ugwu RO, George IO, Jaja TC. Prevalence and risk factors of Helicobacter pylori infection among secondary school adolescents in Port Harcourt Metropolis, Nigeria. Int J Trop Dis Health. 2025;46(5):69–80.

12. Okezie G, Nwobu RAU, Mgbowula I. Prevalence of Helicobacter pylori among clients attending private medical laboratory diagnostic center in Karshi, Abuja, Nigeria. Int J Sci Res Publ. 2020;10(11):489 93.

13. Mynepalli SKC, Maureen O, Mumuni A. Prevalence of Helicobacter pylori and hygiene practices among public secondary school students in Ikeja Local Government Area, Lagos, Nigeria. Health. 2014;6(4):250–8.

14. Bello AK, Borodo MM, Yakasai AM, Tukur AD. Helicobacter pylori antibiotic sensitivity pattern in dyspeptic patients in Kano, Nigeria. S Afr J Infect Dis. 2019;34:125.

15. Olokoba AB, Gashau W, Bwala S, Adamu A, Salawu FK. Helicobacter pylori infection in Nigerians with dyspepsia. Ghana Med J. 2013;47(2):79–81.

16. Jemilohun AC, Otegbayo JA, Ola SO, Oluwasola OA, Akere A. Prevalence of Helicobacter pylori among Nigerian patients with dyspepsia in Ibadan. Pan Afr Med J. 2010;6:18.

17. Ikobah JM, Uhegbu K, Ikwuagwu E, Adedokun F, Akpan FM, Okwong EE, et al. Prevalence and associated risk factors for Helicobacter pylori infection using stool antigen test among children presenting to the outpatient clinic of a tertiary hospital in Nigeria. Calabar J Health Sci. 2023;7:75 83.

FULL TEXT in - | page 81–84

Issue Archive

Volume 2026

Issue 3-Jul-Sep
Issue 2-Apr-Jun
Issue 1-Jan-Mar

Volume 2025

Issue 3-Jul-Sep
Issue 2-Apr-Jun
Issue 1-Jan-Mar

Volume 2024

Issue 3-Jul-Sep
Issue 2-Apr-Jun
Issue 1-Jan-Mar

Volume 2023

Issue 1-Jan-Mar

Volume 2020

Issue 1-Jan-Mar

Volume 2013

Issue 4-Oct-Dec

Copyright © Niger Delta Journal Of Medicine & Medical Research | A Publication Of Nigeria Medical Association Bayelsa State Branch.
All Rights Reserved. P.M.B. 126, Federal Medical Centre, Yenagoa. Bayelsa state Nigeria