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Archive | ISSUE: , Volume: Jul-Sep-2025

DERMOGLYPHIC PATTERN OF PATIENTS WITH SICKLE CELL ANAEMIA IN THE PAEDIATRIC OUTPATIENT DEPARTMENT, UNIVERSITY OF PORT HARCOURT TEACHING HOSPITAL, RIVERS STATE


Author:Aladeh DA, Altraide DD

published date:2025-Sep-10

FULL TEXT in - | page 82–90

Abstract

Background: Dermatoglyphic patterns, which is a noninvasive tool, have been studied by various researchers on the possibility of aiding in diagnosis and management of various genetic disorders. Sickle cell anaemia is an autosomal recessive genetic erythrocyte disorder that can affect multiple organs of the body.

Objectives: This research was carried out to study the characteristic dermatoglyphic pattern in sickle cell disorder and understand if it can serve as a tool for diagnosis of the disease. Methodology: A hospital based cross sectional study was carried out in the paediatric outpatient clinic of University of Port Harcourt Teaching Hospital, Rivers State. A convenience sample of one hundred and thirty sickle cell patients and one hundred and thirty age and sex matched controls who were of the AA and AS genotype were recruited for the study. Palmar dermatoglyphic patterns were studied, fingertip patterns, ‘atd’ angle and ‘a-b’ ridge count were noted in both sickle cell patients and controls and were compared.

Results: In the sickle cell group, whorls (46.58%) had the highest percentage of fingertip pattern in males while loop (40.35%) was the highest in females. Atd angle and a-b ridge count were increased in sickle cell group when compared to controls. Conclusion: The results may help in further research and scientific screening of sickle cell patients.

Keywords: sickle cell anaemia,,,,

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FULL TEXT in - | page 82–90

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