ISSN : 2714-4917


NIGER DELTA JOURNAL OF MEDICINE & MEDICAL RESEARCH

A Publication Of Nigeria Medical Association Bayelsa State Branch

Home About Us For Authors Issues Useful Downloads Contact Information


FAQ NDJMMR

Questions are asked and these questions need answers. This is the reason why this page is created to enable us share few worries!

×
Archive | ISSUE: , Volume: Apr-Jun-2025

THE INTERFACE BETWEEN DEPRESSION AND COMMON CARDIOVASCULAR RISK FACTORS AT THE GRASS ROOT COMMUNITY LEVEL IN SOUTHWESTERN NIGERIA


Author:Oni OO, Ogunwobi O, Akinwusi PO, Owolabi JI, Odeyemi AO, Israel GM1, Ala O, Akande JO, Israel OK, Ajibola I, Aremu AO, Shitu AO

published date:2025-Jul-09

FULL TEXT in - | page 42 - 51

Abstract

Background: Depression is a major cause of morbidity and mortality globally. There is a reciprocal relationship between depression and cardiovascular risk factors. However, the prevalence of depression in the rural areas and the attending cardiovascular risk factors have not been well described.

Methodology: A cross section study of the Ejigbo community was done through convenient sampling. Data was obtained using the Patient Health Questionnaire-9, WHO STEPS and a standard proforma. Ethical approval was obtained from the relevant authorities. Data analysis was done with SPSS version 25.

Results: Two hundred and twenty-five subjects were recruited with 25.8% being males. The total prevalence of depression is 23.2%, with prevalence of mild, moderate and major depression was 12.9%, 7.6% and 2.7% respectively. Those with depression were younger, taller, with higher Body mass index (BMI), higher estimated glomerular filtration rate and a shorter QRS duration. Chest pain, palpitation, breathlessness and intermittent claudication were also more common among the subjects with depression. Those with depression were more likely students, unemployed- unable to work and had a worse New York Heart Association functional score(p=0.001). Diabetes mellitus and Obesity tend to be commoner in those with depression. Depression correlated inversely with age, height, total cholesterol, High Density Lipoprotein cholesterol and directly with BMI, chest pain, palpitations, breathlessness and intermittent claudication. Age, BMI and palpitations were independent determinants of depression in this study.

Conclusion: Depression is prevalent within the community and has significant association with cardiovascular risk factors and symptoms.

Keywords: Depression, Cardiovascular risk, Chronic kidney disease, Diabetes Mellitus, Cholesterol

Cite this article: Oni OO, Ogunwobi O, Akinwusi PO, Owolabi JI, Odeyemi AO, Israel GM, et al. The interface between depression and common cardiovascular risk factors at the grass root community level in Southwestern Nigeria. Niger Delta J Med Med Res. 2025;4(1):42–51.

Keywords: Depression, Cardiovascular risk, Chronic kidney disease, Diabetes Mellitus, Cholesterol

References

1. Hare DL, Toukhsati SR, Johansson P, Jaarsma T. Depression and cardiovascular disease: a clinical review. Eur Heart J. 2014 Jun 1;35(21):1365–1372.

2. Rutledge T, Reis VA, Linke SE, Greenberg BH, Mills PJ. Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol. 2006 Oct 17;48(8):1527–1537.

3. Adewuya AO, Ola BA, Coker OA, Atilola O, Zachariah MP, Olugbile O, et al. Prevalence and associated factors for suicidal ideation in the Lagos State Mental Health Survey, Nigeria. BJPsych open. 2016 Nov;2(6):385–389.

4. Rai? M. Depression and Heart Diseases: Leading Health Problems. Psychiatr Danub. 2017 Dec;29 Suppl 4(Suppl 4):770–777.

5. Amoran O, Lawoyin T, Lasebikan V. Prevalence of depression among adults in Oyo State, Nigeria: A comparative study of rural and urban communities. Aust J Rural Health [Internet]. 2007 Jun 1 [cited 2022 Sep 15];15(3):211–215.

6. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42:1206–1252.

7. DuBois D, DuBois EF. Fifth paper the measurement of the surface area of man. Arch Intern Med. 1915 May 1;15(5):868–881.

8. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge. Clin Chem. 1972 Jun 1;18(6):499–502.

9. Kavey R-E, Daniels SR, Lauer RM, Atkins DL, Hayman LL, Taubert K. American Heart Association Guidelines for Primary Prevention of Atherosclerotic Cardiovascular Disease Beginning in Childhood. Circulation. 2003 Mar 25;107:1562–1566.

10. Ix JH, Wassel CL, Stevens LA, Beck GJ, Froissart M, Navis G, et al. Equations to estimate creatinine excretion rate: The CKD epidemiology collaboration. Clin J Am Soc Nephrol. 2011 Jan 1;6(1):184–191.

11. Baiyewu O, Smith-Gamble V, Lane KA, Gureje O, Gao S, Ogunniyi A, Unverzagt FW, et al. Prevalence estimates of depression in elderly community-dwelling African Americans in Indianapolis and Yoruba in Ibadan, Nigeria. Int psychogeriatrics. 2007 Aug;19(4):679–689.

12. Casey DA. Depression in Older Adults: A Treatable Medical Condition. Prim Care [Internet]. 2017 Sep 1 [cited 2022 Sep 12];44(3):499–510.

13. Olutoki MO, Olagunju AT, Adeyemi JD. Correlates of depressive illness among the elderly in a mixed urban community in Lagos, Nigeria. Aging Ment Health [Internet]. 2014 Jul 4 [cited 2022 Oct 8];18(5):561–569.

14. Katon WJ. The Comorbidity of Diabetes Mellitus and Depression. Am J Med. 2008 Nov 1;121(11):S8–15.

15. B?descu SV, T?taru C, Kobylinska L, Georgescu EL, Zahiu DM, Z?grean AM, et al. The association between Diabetes mellitus and Depression. J Med Life. 2016 Apr 1;9(2):120-125.

16. Bivanco-Lima D, de Souza Santos I, Wang YP, Viana MC, Andrade LH, Lotufo PA, et al. Cardiovascular risk factors and major depressive disorder: a cross sectional study in São Paulo, Brazil. Sao Paulo Med J. 2021;139(4):364–371.

17. Luppino FS, de Wit LM, Bouvy PF, Stijnen T, Cuijpers P, Penninx BW, et al. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry. 2010 Mar;67(3):220–229.

18. Heidenreich PA, Bozkurt B, Aguilar D, Allen LA, Byun JJ, Colvin MM, et al. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022 May 3;145(18).

 

19. Jantaratnotai N, Mosikanon K, Lee Y, McIntyre RS. The interface of depression and obesity. Obes Res Clin Pract. 2017 Jan 1;11(1):1–10.

20. Marazziti D, Rutigliano G, Baroni S, Landi P, Dell’Osso L. Metabolic syndrome and major depression. CNS Spectr. 2014 ;19(4):293–304.

21. Martinac M, Pehar D, Karlovi? D, Babi? D, Mar?inko D, Jakovljevi? M. Metabolic syndrome, activity of the hypothalamic-pituitary-adrenal axis and inflammatory mediators in depressive disorder. Acta Clin Croat. 2014;53(1):55–71.

22. Lochen ML, Rasmussen K. Palpitations and lifestyle: impact of depression and self-rated health. The Nordland Health Study. Scand J Soc Med. 1996; 24(2):140–144.

23. Carnlöf C, Schenck-Gustafsson K, Jensen-Urstad M, Insulander P. Instant electrocardiogram feedback with a new digital technique reduces symptoms caused by palpitations and increases health-related quality of life (the RedHeart study). Eur J Cardiovasc Nurs. 2021 Jun 29;20(5):402–10.

24. Kunwar D, Kunwar R, Shrestha B, Amatya R, Risal A. Depression and Quality of Life among the Chronic Kidney Disease Patients. J Nepal Health Res Counc. 2020 Nov 14;18(3):459–65.

25. Palmer S, Vecchio M, Craig JC, Tonelli M, Johnson DW, Nicolucci A, et al. Prevalence of depression in chronic kidney disease: systematic review and meta analysis of observational studies. Kidney Int. 2013;84(1):179–191.

26. Wang WL, Liang S, Zhu FL, Liu JQ, Wang SY, Chen XM, et al. The prevalence of depression and the association between depression and kidney function and health-related quality of life in elderly patients with chronic kidney disease: A multicenter cross sectional study. Clin Interv Aging. 2019;14:905–913.

FULL TEXT in - | page 42 - 51

Issue Archive

Volume 7 2026

Volume 1 2026

Volume 6 2025

Issue 3-Jul-Sep
Issue 2-Apr-Jun
Issue 1-Jan-Mar

Volume 3 2024

Issue 3-Jul-Sep
Issue 2-Apr-Jun
Issue 1-Jan-Mar

Volume 2 2023

Issue 1-Jan-Mar

Volume 1 2020

Issue 1-Jan-Mar

Volume 4 2013

Issue 4-Oct-Dec

Volume 1 2013

Issue 4-Oct-Dec


Copyright © Niger Delta Journal Of Medicine & Medical Research | A Publication Of Nigeria Medical Association Bayelsa State Branch.
All Rights Reserved. P.M.B. 126, Federal Medical Centre, Yenagoa. Bayelsa state Nigeria