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NIGER DELTA JOURNAL OF MEDICINE & MEDICAL RESEARCH

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Archive | ISSUE: , Volume: Apr-Jun-2024

SEROPREVALENCE OF HEPATITIS B VIRUS AND ASSOCIATED RISK FACTORS AMONG PREGNANT WOMEN ATTENDING ANTENATAL CARE IN MBAITOLI, IMO STATE, NIGERIA


Author:Dike ENM, Uwaezuoke JC, Ekenta DNE

published date:2024-Sep-07

FULL TEXT in - | page 79 - 91

Abstract

Background: Hepatitis B virus (HBV) infection poses a significant global public health challenge, which is exacerbated during
pregnancy.
 
Objectives: The aim of this study was to ascertain the prevalence of HBV, associated risk factors, and its public health
significance among pregnant women in Mbaitoli, Imo State, Nigeria.
 
Methods: Consecutive sampling was employed to conduct a cross-sectional study on 500 expectant women who were
receiving prenatal care in Mbaitoli. Structured questionnaires were implemented to gather data regarding biodemographic
information and risk factors for HBV infection. An immunochromatographic test package was employed to screen for HBsAg.
The data was analysed using IBM® SPSS version 22, which generated frequencies and employed Chi-square tests to
investigate associations. The significance level was established at 0.05, with a 95% confidence interval.
 
Results: Results: A total of 24 pregnant women in Mbaitoli tested positive for HBsAg out of 500 participants, suggesting a
prevalence of HBV of 4.8%. Marital status (p =.020), circumcision (p =.001), HBV vaccination status (p =.011), HIV status (p
=.003), and appointment status (p =.003) were all significant factors that influenced HBV seroprevalence.
 
Conclusion: The HBV prevalence among pregnant women in Mbaitoli is 4.8%, primarily due to horizontal transmission.
Universal neonatal immunisation to be implemented, particularly for the children of HBsAg-positive mothers and no to
female genital mutilation advocated.

Keywords: Hepatitis B, Pregnancy, Hepadnaviridae, Immunization, Seroprevalence

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